PEER REVIEWED PUBLICATIONS


2021 

 

Nicotine inhibits the VTA to Amygdala dopamine pathway to promote anxiety.
Claire Nguyen, Sarah Mondoloni, Tinaïg Le Borgne, Ines Centeno, Maxime Come, Joachim Jehl, Clément Solié, Lauren M Reynolds, Romain Durand-de Cuttoli, Stefania Tolu, Sébastien Valverde, Steve Didienne, Bernadette Hannesse, Jean-François Fiancette, Stéphanie Pons, Uwe Maskos, Véronique Deroche-Gamonet, Deniz Dalkara, Jean-Pierre Hardelin, Alexandre Mourot, Fabio Marti, Philippe Faure
Neuron 2021 doi :10.1016/j.neuron.2021.06.013 Access PDF>

 

Adolescent dopamine development: connecting experience with vulnerability or resilience to psychiatric disease
Lauren M Reynolds, Cecilia Flores
In : Diagnosis and Management of Neurodevelopmental Disorders: The Neuroscience of Development 2021 Academic Press, ISBN 9780128179888. doi: 10.1016/B978-0-12-817988-8.00026-9 PDF>

 

2020 

 

Dopamine Axon Targeting in the Nucleus Accumbens in Adolescence Requires Netrin-1
Santiago Cuesta,Dominique Nouel, Lauren M Reynolds, Alice Morgunova, Angélica Torres-Berrío, Amanda White, Giovanni Hernandez, Helen M Cooper, Cecilia Flores
Frontiers in Cell and Developmental Biology 2020 8:487 doi: 10.3389/fcell.2020.00487 PDF>

 

DCC-dependent developmental effects of abused- versus therapeutic-like amphetamine doses in adolescence 
Santiago Cuesta, Jose Maria Restrepo-Lozano, Christina Popescu, Susan He, Lauren M Reynolds, Sonia Israel, Giovanni Hernandez, Rana Rais, Barbara S Slusher, Cecilia Flores
Addiction Biology 2020 25(4):e12791 doi: 10.1111/adb.12791 PDF>

 

2019 

 

Early adolescence is a critical period for the maturation of inhibitory behavior
Lauren M Reynolds,Leora Yetnikoff, Matthew Pokinko, Michael Wodzinski, Julia G Epelbaum, Laura C Lambert, Marie-Pierre Cossette, Andreas Arvanitogiannis, Cecilia Flores
Cerebral Cortex 2019 29(9):3676-3686 doi: 10.1093/cercor/bhy247 PDF>

 

Guidance Cues: Linking Drug Use in Adolescence with Addiction Vulnerability
Lauren M Reynolds, Cecilia Flores
Neuropsychopharmacology 2019 doi: 10.1038/s41386-018-0221-7 PDF>

 

2018 

 

Non-contingent exposure to amphetamine in adolescence recruits miR-218 to regulate Dcc expression in the VTA
Santiago Cuesta, Jose Maria Restrepo-Lozano, Steven Silvestrin, Daniel Hoops, Dominique Nouel, Angélica Torres-Berrío, Lauren M Reynolds, Andreas Arvanitiogiannis, Cecilia Flores
Neuropsychopharmacology 2018 43(4), 900–911 doi: 10.1038/npp.2017.284 PDF >

 

Featured in NIDA Notes

 

DCC receptors drive prefrontal cortex maturation by determining dopamine axon targeting in adolescence
Lauren M Reynolds, Matthew Pokinko, Angélica Torres-Berrío, Santiago Cuesta, Laura C Lambert, Michael Wodzinski, Esther Del Cid-Pellitero, Colleen Manitt, Paul Krimpenfort, Bryan Kolb, Cecilia Flores 
Biological Psychiatry 2018 83(2): 181–192 doi: 10.1016/j.biopsych.2017.06.009  PDF >
 

 

 

Featured in LaPress (Français)

 

Featured in NIDA News

 

Dopamine development to the orbital prefrontal cortex is protracted and sensitive to amphetamine in adolescence
Daniel Hoops, Lauren M Reynolds, Jose Maria Restrepo-Lozano, Cecilia Flores
eNeuro 2018 doi: 10.1523/ENEURO.0372-17.2017 PDF >

 

2017

 

Advances in understanding and treating mental illness: Proceedings of the 40th Canadian College of Neuropsychopharmacology Annual Meeting Symposia
Catherine P Normandeau†, Darya Naumova†, Shawna L Thompson†, Mohammed Ebrahimzadeh†, Yu Qing Liu†, Lauren Reynolds†, Hong-Yang Ren, Emily R Hawken, Éric C Dumont
Journal of Psychiatry and Neuroscience
2017 Sep;42(5):353-358 doi: 10.1503.jpn/170120   PDF >  
† these authors contributed equally to this work

 

A non-invasive restraining system for awake mouse imaging
Dan Madularu, Axel P Mathieu, Chathura Kumaragamage, Lauren M Reynolds, Jamie Near, Cecilia Flores, M. Natasha Rajah
Journal of Neuroscience Methods 2017 287, 53–57. doi: 10.1016/j.jneumeth.2017.06.008 PDF > 

 

2016

 

dcc haploinsufficiency results in blunted sensitivity to cocaine enhancement of reward seeking
Lauren M Reynolds, Anthony J Gifuni, E. Tess McCrea, Peter Shizgal, Cecilia Flores
Behavioural Brain Research 2016 298A: 27-31 doi: 10.1016/j.bbr.2015.05.020 PDF >
* Invited Submission to Special Issue: Developmental Regulation of Memory in Anxiety and Addiction.

 

2015

 

Amphetamine in adolescence disrupts the development of medial prefrontal cortex dopamine connectivity in a dcc-dependent manner
Lauren M Reynolds, Carolina S Makowski, Sandra V Yogendran, Silke Kiessling, Nicolas Cermakian, Cecilia Flores
Neuropsychopharmacology 2015 Mar;13(40):1101-12 doi: 10.1038/npp.2014.287  PDF > 

 

2014

 

Neural basis of benzodiazepine reward: Requirement for α2-containing GABAA receptors in the nucleus accumbens
Elif Engin, Konstantin I Bakhurin, Kiersten S Smith, Rochelle M Hines, Lauren M Reynolds, W Wannan Tang, Rolf Sprengel, Stephen J Moss, Uwe Rudolph
Neuropsychopharmacology 2014 Jul;39(8):1805-15.  doi: 10.1038/npp.2014.41 PDF > 

 

2012

 

Differential roles of GABAA receptor subtypes in benzodiazepine-induced enhancement of brain-stimulation reward
Lauren M Reynolds, Elif Engin, Gabriella Tantillo, Hew Mun Lau, John W Muschamp, William A Carlezon Jr, Uwe Rudolph . (2012).
Neuropsychopharmacology Oct;37(11):2531-40. doi: 10.1038/npp.2012.115 PDF > 

 

 

See them in Pubmed!